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SEPN — structural market context

Septerna, Inc.

Structural market context from public regulatory and market data, shown with its as-of dates. Descriptive only: nothing on this page is a recommendation, a prediction, or advice to buy or sell any security.

SEPN short interest & days to cover

SHARES SHORT

3.5M

% OF FLOAT

—

DAYS TO COVER

14.2

CHANGE VS PRIOR

+4.7%

FINRA consolidated short interest, reported twice a month and published ~2 weeks after each settlement date. % of float uses reported free float. · as of 2026-07-31 (40d ago)

SEPN fails-to-deliver (FTD)

Settlement date	Failed shares	Price
2026-08-12 · 28d	25K	$47.76
2026-08-11 · 29d	812	$38.85
2026-08-10 · 30d	7	$38.83

SEC fails-to-deliver files, published twice a month with ~6 weeks of delay.

SEPN insider buying and selling (Form 4)

Last 12 months, open-market only: 0 purchases · 4 sales

Insider	Type	Shares	Value	Filed
Long Daniel D. · officer: SVP, Drug Discovery	Sell (S)	3K	$126K	2026-09-03
Third Rock Ventures V, L.P. · 10 percent owner	Sell (S)	147K	$7.4M	2026-08-14
Third Rock Ventures V, L.P. · 10 percent owner	Sell (S)	141	$7K	2026-08-14
RA CAPITAL MANAGEMENT, L.P. · director, 10 percent owner:	Sell (S)	747K	$31.7M	2026-08-14

SEC Form 4 filings, open-market purchases and sales only (codes P and S); grants and option exercises excluded. Attributed public records.

Frequently asked questions

Are insiders buying SEPN?

In the last 12 months of SEC Form 4 filings, SEPN recorded 0 open-market insider purchases and 4 open-market sales (codes P and S; grants and option exercises excluded). These are attributed public records — information, not instruction.

Is this page telling me to buy or sell SEPN?

No. Everything on this page is descriptive, structural market context from public data, shown with its as-of dates. TradeAI News does not issue directional recommendations, price predictions, or buy/sell advice — for any ticker.

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Not financial advice. Trading involves risk. Descriptive structural context, never a recommendation.